Strategies to obtain robust designs for toxicological tests
S. Pozuelo Campos, M. Amo Salas, V. M. Casero Alonso
Toxicological tests are widely used to study toxicity in aquatic environments. Reproduction is a possible endpoint of this type of experiment, whose response variable is given by counts. There is literature about the suitable probability distribution to be used for analyzing these data. In the theory of optimal experimental design, the assumption of this probability distribution is essential, and when this assumption is not adequate, there may be a loss of efficiency in the design obtained. The main objective of this study is to propose robust designs when there is uncertainty about the probability distribution of the response variable. We introduce and compare three different strategies for attaining this goal and they are applied to toxicological tests based on Ceriodaphnia dubia and Lemna minor. In addition, a simulation study is performed to test the estimation properties of the robust designs obtained.
Keywords: D-optimality, Elemental Information Matrix, Exponential Family Distribution, Linear Logistic model.
Scheduled
GT07 Design of Experiments II
June 8, 2022 4:00 PM
Conference hall
Other papers in the same session
C. de la Calle Arroyo, M. González Fernández, J. López Fidalgo, L. J. Rodríguez-Aragón
P. urruchi, J. López Fidalgo
J. M. Rodriguez Diaz
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6/8/22
Visit Alhambra
Tomorrow, Thursday, we will visit the Alhambra. 1. At 7:00 p.m., buses will start leaving from the door of the Hotel Granada Center (in front of the door of the Faculty of Sciences) 2. Upon arrival, groups with guides will be organized. 3. There will be groups in English language. These groups will wait at the destination until the arrival of all buses. 4. After the visit to the Alhambra we will walk to the Carmen de los Mártires to have a cocktail. 5. On the way back, we can go back by bus, which will leave from the same place where they left us at the Alhambra. 6. Although the way to the Alhambra by bus seems long, it really is close to the city. We invite you, whoever wishes, to go down for a pleasant walk. 7. Do not forget to take your Alhambra ticket and your identity card or passport. The document must be the same whose number matches the ticket number you have.
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5/31/22
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5/27/22
Gala Dinner
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5/23/22
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To access the Alhambra on the visit on Thursday 9, it is obligatory to present the identification document whose reference was sent to the organization (eurocongress)
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5/16/22
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